INTRODUCTION Coronaviruses are important human and animal pathogens. At the end of 2019, a novel coronaviruswas identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei Province ofChina. It rapidly spread, resulting in an epidemicthroughout China, followed by an increasing numberof cases in other countries throughout the world. In February 2020, the World Health Organizationdesignated the disease COVID-19, which stands for coronavirus disease 2019.The virus thatcauses COVID-19 is designated severe acute respiratory syndrome coronavirus 2(SARS-CoV-2);previously, it was referred to as 2019-nCoV.Understanding of COVID-19 is evolving. Interim guidance has been issued by the World HealthOrganization and by the United States Centers for Disease Control and Prevention.Links tothese and other related society guidelines are found elsewhere. (See 'Society guideline links' below.)This topic will discuss the epidemiology, clinical features, diagnosis, management, and prevention ofCOVID-19
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